Efficacy of a nasal spray containing N-acetylcysteine in hypertonic solution in the treatment of nonallergic chronic rhinitis with goblet cell metaplasia.

Maffezzoni, E; Notargiacomo, M; Agostini, S; Gelardi, M

Maffezzoni, E; Notargiacomo, M; Agostini, S; Gelardi, M.

Affiliation

Maffezzoni E; Rhinocytoallergology Unit, Istituto Figlie di San Camillo, Cremona, Italy.
Notargiacomo M; Otorhinolaryngology Unit, Melzo Hospital, Milan, Italy.
Agostini S; Scientific Direction, Pharma Line, Milan, Italy.
Gelardi M; Unit of Otolaryngology, University of Foggia, Foggia, Italy.

J Biol Regul Homeost Agents ; 34(6): 2345-2352, 2020.

Article in En | MEDLINE | ID: mdl-33415969

Subject(s)

Rhinitis; Acetylcysteine/therapeutic use; Administration, Intranasal; Chronic Disease; Goblet Cells; Humans; Hypertonic Solutions/therapeutic use; Metaplasia/complications; Nasal Mucosa; Nasal Sprays; Rhinitis/complications; Rhinitis/drug therapy

Key words

N-acetylcysteine; chronic rhinitis; goblet cell metaplasia; hypertonic saline solution; nasal cytology; topical therapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhinitis Limits: Humans Language: En Journal: J Biol Regul Homeost Agents Journal subject: BIOLOGIA / BIOQUIMICA Year: 2020 Document type: Article Affiliation country: Italy Country of publication: Italy

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