Development of a zebrafish screening model for diabetic retinopathy induced by hyperglycemia: Reproducibility verification in animal model.

Lee, Yujin; Yang, Jaewook

Lee, Yujin; Yang, Jaewook.

Affiliation

Lee Y; Inje University Busan Paik Hospital, Department of Ophthalmology. 81, Jinsa-ro 83beon-gil, Busanjin-gu, Busan, South Korea.
Yang J; Inje University Busan Paik Hospital, Department of Ophthalmology. 81, Jinsa-ro 83beon-gil, Busanjin-gu, Busan, South Korea; EYEBIOKOREA, 81, Jinsa-ro 83beon-gil, Busanjin-gu, Busan, South Korea. Electronic address: oculoplasty@gmail.com.

Biomed Pharmacother ; 135: 111201, 2021 Mar.

Article in En | MEDLINE | ID: mdl-33421732

Subject(s)

Diabetic Retinopathy/etiology; Glucose; Hyperglycemia/complications; Retinal Neovascularization; Retinal Vessels/pathology; Angiogenesis Inhibitors/pharmacology; Animals; Animals, Genetically Modified; Cytokines/genetics; Cytokines/metabolism; Diabetic Retinopathy/drug therapy; Diabetic Retinopathy/metabolism; Diabetic Retinopathy/pathology; Disease Models, Animal; Hyperglycemia/chemically induced; Inflammation Mediators/metabolism; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins/pharmacology; Retinal Vessels/drug effects; Retinal Vessels/metabolism; Zebrafish

Key words

Diabetic retinopathy; Eye; Inflammation; Zebrafish

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Vessels / Retinal Neovascularization / Diabetic Retinopathy / Glucose / Hyperglycemia Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2021 Document type: Article Affiliation country: South Korea Country of publication: France

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