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Brazilian recommendations for the use of nonsteroidal anti-inflammatory drugs in patients with axial spondyloarthritis.
da Cruz Lage, Ricardo; Marques, Claudia Diniz Lopes; Oliveira, Thauana Luiza; Resende, Gustavo Gomes; Kohem, Charles Lubianca; Saad, Carla Gonçalves; Ximenes, Antônio Carlos; Gonçalves, Célio Roberto; Bianchi, Washington Alves; de Souza Meirelles, Eduardo; Keiserman, Mauro Waldemar; Chiereghin, Adriano; Campanholo, Cristiano Barbosa; Lyrio, André Marun; Schainberg, Cláudia Goldenstein; Pieruccetti, Lenise Brandao; Yazbek, Michel Alexandre; Palominos, Penelope Esther; Goncalves, Rafaela Silva Guimarães; Assad, Rodrigo Luppino; Bonfiglioli, Rubens; Lima, Sônia Maria Alvarenga Anti Loduca; Carneiro, Sueli; Azevedo, Valderílio Feijó; Albuquerque, Cleandro Pires; Bernardo, Wanderley Marques; Sampaio-Barros, Percival Degrava; de Medeiros Pinheiro, Marcelo.
Affiliation
  • da Cruz Lage R; Universidade Federal de Minas Gerais (UFMG), Alameda Álvaro Celso 175, Ambulatório Bias Fortes, 2° andar, Belo Horizonte, MG, 30150-260, Brazil. ricolage@gmail.com.
  • Marques CDL; Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
  • Oliveira TL; Universidade Federal de São Paulo (UNIFESP/ EPM), São Paulo, SP, Brazil.
  • Resende GG; Universidade Federal de Minas Gerais (UFMG), Alameda Álvaro Celso 175, Ambulatório Bias Fortes, 2° andar, Belo Horizonte, MG, 30150-260, Brazil.
  • Kohem CL; Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
  • Saad CG; Universidade de São Paulo (USP), São Paulo, SP, Brazil.
  • Ximenes AC; Hospital Estadual Geral de Goiania (HGG), Goiânia, Brazil.
  • Gonçalves CR; Universidade de São Paulo (USP), São Paulo, SP, Brazil.
  • Bianchi WA; Santa Casa de Misericórdia (SCM) do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
  • de Souza Meirelles E; Universidade de São Paulo (USP), São Paulo, SP, Brazil.
  • Keiserman MW; Pontifícia Universidade Católica (PUC) de Porto Alegre, Porto Alegre, RS, Brazil.
  • Chiereghin A; Pontifícia Universidade Católica (PUC) de Sorocaba, Sorocaba, SP, Brazil.
  • Campanholo CB; Santa Casa de Misericórdia (SCM) de São Paulo, São Paulo, SP, Brazil.
  • Lyrio AM; Pontifícia Universidade Católica (PUC) de Campinas, Campinas, SP, Brazil.
  • Schainberg CG; Universidade de São Paulo (USP), São Paulo, SP, Brazil.
  • Pieruccetti LB; Hospital Heliópolis, São Paulo, SP, Brazil.
  • Yazbek MA; Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.
  • Palominos PE; Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
  • Goncalves RSG; Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
  • Assad RL; Ribeirão Preto, Ribeirão Preto, Brazil.
  • Bonfiglioli R; Pontifícia Universidade Católica (PUC) de Campinas, Campinas, SP, Brazil.
  • Lima SMAAL; Hospital do Servidor Público do Estado de São Paulo, São Paulo, SP, Brazil.
  • Carneiro S; Universidade Federal do Rio De Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
  • Azevedo VF; Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil.
  • Albuquerque CP; Universidade de Brasília (UnB), Brasília, DF, Brazil.
  • Bernardo WM; Universidade de São Paulo (USP), São Paulo, SP, Brazil.
  • Sampaio-Barros PD; Universidade de São Paulo (USP), São Paulo, SP, Brazil.
  • de Medeiros Pinheiro M; Universidade Federal de São Paulo (UNIFESP/ EPM), São Paulo, SP, Brazil.
Adv Rheumatol ; 61(1): 4, 2021 01 19.
Article in En | MEDLINE | ID: mdl-33468245
Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonsteroidal anti-inflammatory drugs (NSAIDs) have been the basis for the pharmacological treatment of patients with axial spondyloarthritis (axSpA). However, the emergence of the immunobiologic agents brought up the discussion about the role of NSAIDs in the management of these patients. The objective of this guideline is to provide recommendations for the use of NSAIDs for the treatment of axSpA. A panel of experts from the Brazilian Society of Rheumatology conducted a systematic review and meta-analysis of randomized clinical trials for 15 predefined questions. The Grading of Recommendations, Assessment, Development and Evaluation methodology to assess the quality of evidence and formulate recommendations were used, and at least 70% agreement of the voting panel was needed. Fourteen recommendations for the use of NSAIDs in the treatment of patients with axSpA were elaborated. The purpose of these recommendations is to support clinicians' decision making, without taking out his/her autonomy when prescribing for an individual patient.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Spondylarthritis Type of study: Clinical_trials / Guideline / Prognostic_studies / Qualitative_research / Systematic_reviews Limits: Humans Country/Region as subject: America do sul / Brasil Language: En Journal: Adv Rheumatol Year: 2021 Document type: Article Affiliation country: Brazil Country of publication: United kingdom
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Spondylarthritis Type of study: Clinical_trials / Guideline / Prognostic_studies / Qualitative_research / Systematic_reviews Limits: Humans Country/Region as subject: America do sul / Brasil Language: En Journal: Adv Rheumatol Year: 2021 Document type: Article Affiliation country: Brazil Country of publication: United kingdom