Polyhexamethylene Guanidine Phosphate Induces Apoptosis through Endoplasmic Reticulum Stress in Lung Epithelial Cells.

Jeong, Mi Ho; Jeon, Mi Seon; Kim, Ga Eun; Kim, Ha Ryong

Jeong, Mi Ho; Jeon, Mi Seon; Kim, Ga Eun; Kim, Ha Ryong.

Affiliation

Jeong MH; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Jeon MS; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Kim GE; College of Pharmacy, Daegu Catholic University, Gyeongsan 38430, Korea.
Kim HR; College of Pharmacy, Daegu Catholic University, Gyeongsan 38430, Korea.

Int J Mol Sci ; 22(3)2021 Jan 26.

Article in En | MEDLINE | ID: mdl-33530568

Subject(s)

Alveolar Epithelial Cells/drug effects; Alveolar Epithelial Cells/metabolism; Apoptosis/drug effects; Endoplasmic Reticulum Stress/drug effects; Guanidines/pharmacology; A549 Cells; Animals; Cells, Cultured; Endoplasmic Reticulum/drug effects; Endoplasmic Reticulum/metabolism; Flow Cytometry; Humans; Mice; Phosphorylation; Protein Transport; Pulmonary Fibrosis/etiology; Pulmonary Fibrosis/metabolism; Pulmonary Fibrosis/pathology; Signal Transduction

Key words

ER stress; PHMG-p; apoptosis; lung fibrosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Alveolar Epithelial Cells / Endoplasmic Reticulum Stress / Guanidines Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Country of publication: Switzerland

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