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HMGCS1 drives drug-resistance in acute myeloid leukemia through endoplasmic reticulum-UPR-mitochondria axis.
Zhou, Cheng; Li, Jue; Du, Juan; Jiang, Xinya; Xu, Xuejun; Liu, Yi; He, Qun; Liang, Hui; Fang, Peng; Zhan, Huien; Zeng, Hui.
Affiliation
  • Zhou C; Department of Hematology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510630, China; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
  • Li J; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
  • Du J; Department of Hematology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510630, China.
  • Jiang X; Department of Hematology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510630, China; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
  • Xu X; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
  • Liu Y; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
  • He Q; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
  • Liang H; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
  • Fang P; Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
  • Zhan H; Department of Hematology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510630, China. Electronic address: zhanhuien@163.com.
  • Zeng H; Department of Hematology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510630, China. Electronic address: androps2011@hotmail.com.
Biomed Pharmacother ; 137: 111378, 2021 May.
Article in En | MEDLINE | ID: mdl-33601148

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Signal Transduction / Drug Resistance, Neoplasm / Endoplasmic Reticulum / Unfolded Protein Response / Hydroxymethylglutaryl-CoA Synthase / Mitochondria Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2021 Document type: Article Affiliation country: China Country of publication: France

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Signal Transduction / Drug Resistance, Neoplasm / Endoplasmic Reticulum / Unfolded Protein Response / Hydroxymethylglutaryl-CoA Synthase / Mitochondria Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2021 Document type: Article Affiliation country: China Country of publication: France