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Suppression of Myocardial Hypoxia-Inducible Factor-1α Compromises Metabolic Adaptation and Impairs Cardiac Function in Patients With Cyanotic Congenital Heart Disease During Puberty.
Liu, Yiwei; Luo, Qipeng; Su, Zhanhao; Xing, Junyue; Wu, Jinlin; Xiang, Li; Huang, Yuan; Pan, Haizhou; Wu, Xie; Zhang, Xiaoling; Li, Jun; Yan, Fuxia; Zhang, Hao.
Affiliation
  • Liu Y; Heart Center and Shanghai Institute of Pediatric Congenital Heart Disease, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China (Y.L., J.X., L.X., H.Z.).
  • Luo Q; Shanghai Clinical Research Center for Rare Pediatric Diseases, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China (Y.L., H.Z.).
  • Su Z; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Q.L., Z.S., Y.H., H.P., X.W., X.Z., J.L., F.Y.).
  • Xing J; Department of Anesthesia, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Q.L., X.W., F.Y.).
  • Wu J; Pain Medicine Center, Peking University Third Hospital, Beijing, China (Q.L.).
  • Xiang L; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Q.L., Z.S., Y.H., H.P., X.W., X.Z., J.L., F.Y.).
  • Huang Y; Heart Center and Shanghai Institute of Pediatric Congenital Heart Disease, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China (Y.L., J.X., L.X., H.Z.).
  • Pan H; Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China (J.W.).
  • Wu X; Heart Center and Shanghai Institute of Pediatric Congenital Heart Disease, Shanghai Children's Medical Center, National Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China (Y.L., J.X., L.X., H.Z.).
  • Zhang X; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Q.L., Z.S., Y.H., H.P., X.W., X.Z., J.L., F.Y.).
  • Li J; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Q.L., Z.S., Y.H., H.P., X.W., X.Z., J.L., F.Y.).
  • Yan F; Children's Heart Center, the Second Affiliated Hospital and Yuying Children's Hospital, Institute of Cardiovascular Development and Translational Medicine, Wenzhou Medical University, Zhejiang, China (H.P.).
  • Zhang H; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Q.L., Z.S., Y.H., H.P., X.W., X.Z., J.L., F.Y.).
Circulation ; 143(23): 2254-2272, 2021 06 08.
Article in En | MEDLINE | ID: mdl-33663226
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hypoxia-Inducible Factor 1, alpha Subunit / Heart Defects, Congenital / Myocardium Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Circulation Year: 2021 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hypoxia-Inducible Factor 1, alpha Subunit / Heart Defects, Congenital / Myocardium Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Circulation Year: 2021 Document type: Article Country of publication: United States