Carboxymethylated chitosan alleviated oxidative stress injury in retinal ganglion cells via IncRNA-THOR/IGF2BP1 axis.

Wu, Xiaoli; Liu, Yingying; Ji, Yun

Wu, Xiaoli; Liu, Yingying; Ji, Yun.

Affiliation

Wu X; Ophthalmology Department, Shandong Rongjun General Hospital, Jinan, Shandong Province, China.
Liu Y; Neurology Department, Shandong Rongjun General Hospital, Jinan, Shandong Province, China.
Ji Y; Yantai Laiyang Central Hospital, Yantai, Shandong, China. wxli1980@126.com.

Genes Genomics ; 43(6): 643-651, 2021 06.

Article in En | MEDLINE | ID: mdl-33811613

Subject(s)

Glaucoma/drug therapy; Oxidative Stress/genetics; RNA, Long Noncoding/genetics; RNA-Binding Proteins/genetics; Antioxidants/pharmacology; Apoptosis/drug effects; Axons/drug effects; Cell Line; Cell Proliferation/drug effects; Cell Proliferation/genetics; Cell Survival/drug effects; Cell Survival/genetics; Chitosan/chemistry; Chitosan/pharmacology; Cycloheximide/pharmacology; Glaucoma/genetics; Glaucoma/pathology; Humans; Hydrogen Peroxide/chemistry; Retinal Ganglion Cells/drug effects; Retinal Ganglion Cells/pathology; Signal Transduction/drug effects

Key words

Carboxymethylated chitosan (CMCS); IGF2BP1; LncRNA THOR; Oxidative stress; RGCs

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glaucoma / RNA-Binding Proteins / Oxidative Stress / RNA, Long Noncoding Limits: Humans Language: En Journal: Genes Genomics Year: 2021 Document type: Article Affiliation country: China Country of publication:

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