Association between aging-dependent gut microbiome dysbiosis and dry eye severity in C57BL/6 male mouse model: a pilot study.

Yoon, Chang Ho; Ryu, Jin Suk; Moon, Jayoon; Kim, Mee Kum

Yoon, Chang Ho; Ryu, Jin Suk; Moon, Jayoon; Kim, Mee Kum.

Affiliation

Yoon CH; Department of Ophthalmology, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Ryu JS; Department of Ophthalmology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Moon J; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Kim MK; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

BMC Microbiol ; 21(1): 106, 2021 04 09.

Article in En | MEDLINE | ID: mdl-33832437

Subject(s)

Dry Eye Syndromes/complications; Dysbiosis/complications; Dysbiosis/microbiology; Gastrointestinal Microbiome/physiology; Aging; Animals; Bacteria/genetics; Biodiversity; Disease Models, Animal; Feces/microbiology; Male; Mice; Mice, Inbred C57BL; Pilot Projects; RNA, Ribosomal, 16S/genetics; Severity of Illness Index

Key words

16S rRNA; Aging; Dry eye; Microbiome; Paraprevotella

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dry Eye Syndromes / Dysbiosis / Gastrointestinal Microbiome Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: BMC Microbiol Journal subject: MICROBIOLOGIA Year: 2021 Document type: Article Country of publication: United kingdom

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