Wheat Germ Agglutinin-Conjugated Disulfide Cross-Linked Alginate Nanoparticles as a Docetaxel Carrier for Colon Cancer Therapy.

Chiu, Hock Ing; Lim, Vuanghao

Chiu, Hock Ing; Lim, Vuanghao.

Affiliation

Chiu HI; Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang, Malaysia.
Lim V; Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang, Malaysia.

Int J Nanomedicine ; 16: 2995-3020, 2021.

Article in En | MEDLINE | ID: mdl-33911862

Subject(s)

Colonic Neoplasms/drug therapy; Docetaxel/administration & dosage; Drug Carriers/chemistry; Nanoparticles/administration & dosage; Wheat Germ Agglutinins/chemistry; Alginates/chemistry; Animals; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/pharmacokinetics; Colonic Neoplasms/pathology; Disulfides/chemistry; Docetaxel/pharmacokinetics; Drug Carriers/administration & dosage; Dynamic Light Scattering; HT29 Cells; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Mice; Microscopy, Electron, Scanning; Nanoparticles/chemistry

Key words

HT-29; anticancer drug; polymeric nanocarrier; targeting ligand

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Wheat Germ Agglutinins / Drug Carriers / Colonic Neoplasms / Nanoparticles / Docetaxel Limits: Animals / Humans Language: En Journal: Int J Nanomedicine Year: 2021 Document type: Article Affiliation country: Malaysia Country of publication: New Zealand

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