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Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways.
Ho, Won Jin; Erbe, Rossin; Danilova, Ludmila; Phyo, Zaw; Bigelow, Emma; Stein-O'Brien, Genevieve; Thomas, Dwayne L; Charmsaz, Soren; Gross, Nicole; Woolman, Skylar; Cruz, Kayla; Munday, Rebecca M; Zaidi, Neeha; Armstrong, Todd D; Sztein, Marcelo B; Yarchoan, Mark; Thompson, Elizabeth D; Jaffee, Elizabeth M; Fertig, Elana J.
Affiliation
  • Ho WJ; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Erbe R; The Johns Hopkins Cancer Convergence Institute, Baltimore, USA.
  • Danilova L; Skip Viragh Center for Pancreatic Cancer, Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, 4M07 Bunting Blaustein Cancer Research Building, 1650 Orleans Street, Baltimore, MD, 21287, USA.
  • Phyo Z; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Bigelow E; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, USA.
  • Stein-O'Brien G; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Thomas DL; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Charmsaz S; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Gross N; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, USA.
  • Woolman S; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Cruz K; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, USA.
  • Munday RM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Zaidi N; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Armstrong TD; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Sztein MB; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Yarchoan M; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Thompson ED; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, USA.
  • Jaffee EM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 550 N Broadway Suite 1101E, Baltimore, MD, 21209, USA.
  • Fertig EJ; Skip Viragh Center for Pancreatic Cancer, Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, 4M07 Bunting Blaustein Cancer Research Building, 1650 Orleans Street, Baltimore, MD, 21287, USA.
Genome Biol ; 22(1): 154, 2021 05 13.
Article in En | MEDLINE | ID: mdl-33985562

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Signal Transduction / Genomics / Tumor Microenvironment / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Genome Biol Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Signal Transduction / Genomics / Tumor Microenvironment / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Genome Biol Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom