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DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function.
Matías-García, Pamela R; Ward-Caviness, Cavin K; Raffield, Laura M; Gao, Xu; Zhang, Yan; Wilson, Rory; Gào, Xin; Nano, Jana; Bostom, Andrew; Colicino, Elena; Correa, Adolfo; Coull, Brent; Eaton, Charles; Hou, Lifang; Just, Allan C; Kunze, Sonja; Lange, Leslie; Lange, Ethan; Lin, Xihong; Liu, Simin; Nwanaji-Enwerem, Jamaji C; Reiner, Alex; Shen, Jincheng; Schöttker, Ben; Vokonas, Pantel; Zheng, Yinan; Young, Bessie; Schwartz, Joel; Horvath, Steve; Lu, Ake; Whitsel, Eric A; Koenig, Wolfgang; Adamski, Jerzy; Winkelmann, Juliane; Brenner, Hermann; Baccarelli, Andrea A; Gieger, Christian; Peters, Annette; Franceschini, Nora; Waldenberger, Melanie.
Affiliation
  • Matías-García PR; TUM School of Medicine, Technical University of Munich, Munich, Germany. pamela.matias@helmholtz-muenchen.de.
  • Ward-Caviness CK; Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich/Neuherberg, Germany. pamela.matias@helmholtz-muenchen.de.
  • Raffield LM; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich/Neuherberg, Germany. pamela.matias@helmholtz-muenchen.de.
  • Gao X; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. pamela.matias@helmholtz-muenchen.de.
  • Zhang Y; Center for Public Health and Environmental Assessment, US Environmental Protection Agency, Chapel Hill, NC, USA.
  • Wilson R; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
  • Gào X; Laboratory of Precision Environmental Health, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • Nano J; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Bostom A; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Colicino E; Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich/Neuherberg, Germany.
  • Correa A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich/Neuherberg, Germany.
  • Coull B; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Eaton C; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich/Neuherberg, Germany.
  • Hou L; German Center for Diabetes Research (DZD), Neuherberg, Germany.
  • Just AC; Center For Primary Care and Prevention, Memorial Hospital of Rhode Island, Pawtucket, RI, USA.
  • Kunze S; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Lange L; Departments of Medicine and Pediatrics, University of Mississippi Medical Center, Jackson, MS, USA.
  • Lange E; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Lin X; Center For Primary Care and Prevention, Memorial Hospital of Rhode Island, Pawtucket, RI, USA.
  • Liu S; Department of Family Medicine, Warren Alpert Medical School, Brown University, Providence, RI, USA.
  • Nwanaji-Enwerem JC; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Reiner A; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Shen J; Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich/Neuherberg, Germany.
  • Schöttker B; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich/Neuherberg, Germany.
  • Vokonas P; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
  • Zheng Y; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
  • Young B; Veterans Affairs Normative Aging Study, Veterans Affairs Boston Healthcare System, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Schwartz J; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.
  • Horvath S; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Lu A; Department of Epidemiology, University of Washington, Seattle, WA, USA.
  • Whitsel EA; Department of Population Health Sciences, School of Medicine, University of Utah, Salt Lake City, UT, USA.
  • Koenig W; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Adamski J; Network Aging Research, University of Heidelberg, Heidelberg, Germany.
  • Winkelmann J; Veterans Affairs Normative Aging Study, Veterans Affairs Boston Healthcare System, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Brenner H; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Baccarelli AA; Nephrology, Hospital and Specialty Medicine and Center for Innovation for Veteran-Centered and Value Driven Care, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
  • Gieger C; Division of Nephrology, Kidney Research Institute, University of Washington, Seattle, WA, USA.
  • Peters A; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Franceschini N; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Waldenberger M; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Clin Epigenetics ; 13(1): 121, 2021 06 02.
Article in En | MEDLINE | ID: mdl-34078457
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mortality / Aging, Premature / Renal Insufficiency Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Epigenetics Year: 2021 Document type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mortality / Aging, Premature / Renal Insufficiency Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Epigenetics Year: 2021 Document type: Article Affiliation country: Germany