Pharmacokinetics of Five Alkaloids and their Metabolites in Normal and Diabetic Rats after Oral Administration of Rhizoma coptidis.

Feng, Xinchi; Wang, Kun; Cao, Shijie; Ding, Liqin; Qiu, Feng

Feng, Xinchi; Wang, Kun; Cao, Shijie; Ding, Liqin; Qiu, Feng.

Affiliation

Feng X; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Wang K; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Cao S; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Ding L; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Qiu F; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Planta Med ; 88(11): 921-932, 2022 Sep.

Article in En | MEDLINE | ID: mdl-34111890

Subject(s)

Alkaloids; Berberine Alkaloids; Berberine; Coptis; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Administration, Oral; Animals; Berberine Alkaloids/metabolism; Coptis/metabolism; Diabetes Mellitus, Experimental/drug therapy; Drugs, Chinese Herbal/pharmacology; Glucuronides; Rats

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Berberine / Berberine Alkaloids / Drugs, Chinese Herbal / Coptis / Diabetes Mellitus, Experimental / Alkaloids Limits: Animals Language: En Journal: Planta Med Year: 2022 Document type: Article Affiliation country: China Country of publication: Germany

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