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Coinfection pulmonary mucormycosis and aspergillosis with disseminated mucormycosis involving gastrointestinalin in an acute B-lymphoblastic leukemia patient.
Hu, Zhi-Min; Wang, Lan-Lan; Zou, Liang; Chen, Zhong-Ju; Yi, Yang; Meng, Qin-Bin; Feng, Yan.
Affiliation
  • Hu ZM; Section of Clinical Microbiology and Molecular Biology, Department of Laboratory Medicine, Wuhan No. 1 Hospital, 215 Zhongshan Ave, Wuhan City, 430022, Hubei, China.
  • Wang LL; Section of Hematology, Department of Internal Medicine, Wuhan No. 1 Hospital, 215 Zhongshan Ave, Wuhan City, 430022, Hubei, China.
  • Zou L; Section of Hematology, Department of Internal Medicine, Wuhan No. 1 Hospital, 215 Zhongshan Ave, Wuhan City, 430022, Hubei, China. zozozou@qq.com.
  • Chen ZJ; Section of Clinical Microbiology, Department of Laboratory Medicine, Tongji Hospital, Tongji Medicine College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, China.
  • Yi Y; Department of Radiology, Wuhan No. 1 Hospital, 215 Zhongshan Ave, Wuhan City, 430022, Hubei, China.
  • Meng QB; Division of Gastrointestinal Surgery, Department of Surgery, Wuhan No. 1 Hospital, 215 Zhongshan Ave, Wuhan City, 430022, Hubei, China.
  • Feng Y; Department of Pathology, Wuhan No. 1 Hospital, 215 Zhongshan Ave, Wuhan City, 430022, Hubei, China.
Braz J Microbiol ; 52(4): 2063-2068, 2021 Dec.
Article in En | MEDLINE | ID: mdl-34218427
Pulmonary mucormycosis and aspergillosis with disseminated mucormycosis involving gastrointestinalin is a very rare but lethal infection leading to extreme mortality. Herein, we present a unique case of pulmonary coinfection with Cunninghamella bertholletiae and Aspergillus flavus, with disseminated mucormycosis involving the jejunum caused by C. bertholletiae in an acute B-lymphocytic leukemia (B-ALL) patient with familial diabetes. Early administration of active antifungal agents at optimal doses and complete resection of all infected tissues led to improved therapeutic outcomes.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cunninghamella / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Pulmonary Aspergillosis / Coinfection / Lung Diseases / Mucormycosis Type of study: Diagnostic_studies Limits: Female / Humans / Middle aged Language: En Journal: Braz J Microbiol Year: 2021 Document type: Article Affiliation country: China Country of publication: Brazil

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cunninghamella / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Pulmonary Aspergillosis / Coinfection / Lung Diseases / Mucormycosis Type of study: Diagnostic_studies Limits: Female / Humans / Middle aged Language: En Journal: Braz J Microbiol Year: 2021 Document type: Article Affiliation country: China Country of publication: Brazil