Your browser doesn't support javascript.
loading
Catecholamine levels in the brain of SART (repeated cold)-stressed rats.
Hata, T; Kita, T; Kamanaka, Y; Honda, S; Kakehi, K; Kawabata, A; Itoh, E.
Affiliation
  • Hata T; Department of Pharmacology, Faculty of Pharmacy, Kinki University, Osaka, Japan.
J Auton Pharmacol ; 7(3): 257-66, 1987 Sep.
Article in En | MEDLINE | ID: mdl-3429462
1 The catecholamine levels in the brains of SART (specific alternation of rhythm in temperature)-stressed (repeated cold-stressed) rats with vagotonic-type dysautonomia, were examined by high performance liquid chromatography with electrochemical detection techniques. 2 The cerebral cortex, hypothalamus and hippocampus of the SART-stressed rats had increased levels of noradrenaline. All brain areas examined showed increased levels of dopamine. 3 These increased catecholamine levels were still maintained by day 10 of SART stress. 4 Among brain areas examined, the hypothalamus showed most rapid change. 5 Cold-stressed rats showed increased noradrenaline levels only in the basal ganglia and dopamine levels in the hippocampus. 6 Rats suffering from restraint and water immersion stress showed decreased noradrenaline levels and increased dopamine levels. 7 These results suggest that SART-stressed animals are in a disease state differing from that of other so-called stressed animals, and changes in the hypothalamus give rise to the various symptoms in SART-stressed animals.
Subject(s)
Search on Google
Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Brain / Catecholamines / Cold Temperature Limits: Animals Language: En Journal: J Auton Pharmacol Year: 1987 Document type: Article Affiliation country: Japan Country of publication: United kingdom
Search on Google
Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Brain / Catecholamines / Cold Temperature Limits: Animals Language: En Journal: J Auton Pharmacol Year: 1987 Document type: Article Affiliation country: Japan Country of publication: United kingdom