Methylation of Promoters of Apoptosis-Related Genes in Blood Lymphocytes of Workers Exposed to Occupational External Irradiation.

Isubakova, D S; Tsymbal, O S; Bronikovskaya, E V; Litviakov, N V; Milto, I V; Takhauov, R Ð

Isubakova, D S; Tsymbal, O S; Bronikovskaya, E V; Litviakov, N V; Milto, I V; Takhauov, R Ð.

Affiliation

Isubakova DS; Seversk Biophysical Research Center, Federal Medical-Biological Agency of Russia, Seversk, Russia. sbnc@fmbamail.ru.
Tsymbal OS; Seversk Biophysical Research Center, Federal Medical-Biological Agency of Russia, Seversk, Russia.
Bronikovskaya EV; Seversk Biophysical Research Center, Federal Medical-Biological Agency of Russia, Seversk, Russia.
Litviakov NV; Seversk Biophysical Research Center, Federal Medical-Biological Agency of Russia, Seversk, Russia.
Milto IV; Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
Takhauov RÐ; Seversk Biophysical Research Center, Federal Medical-Biological Agency of Russia, Seversk, Russia.

Bull Exp Biol Med ; 171(3): 357-361, 2021 Jul.

Article in En | MEDLINE | ID: mdl-34297287

Subject(s)

Chromosome Aberrations/radiation effects; DNA Methylation; Epigenesis, Genetic; Lymphocytes/radiation effects; Occupational Exposure/adverse effects; Promoter Regions, Genetic; Radiation Exposure/adverse effects; Aged; Apoptosis/genetics; Apoptosis Regulatory Proteins/genetics; Apoptosis Regulatory Proteins/metabolism; Apoptotic Protease-Activating Factor 1/genetics; Apoptotic Protease-Activating Factor 1/metabolism; BH3 Interacting Domain Death Agonist Protein/genetics; BH3 Interacting Domain Death Agonist Protein/metabolism; Chromosome Aberrations/classification; Gamma Rays/adverse effects; Humans; Lymphocytes/metabolism; Lymphocytes/pathology; Male; Middle Aged; Radiometry; Repressor Proteins/genetics; Repressor Proteins/metabolism; Siberia; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/metabolism; bcl-2-Associated X Protein/genetics; bcl-2-Associated X Protein/metabolism; bcl-Associated Death Protein/genetics; bcl-Associated Death Protein/metabolism

Key words

DNA methylation; a promoter; apoptosis; chromosomal aberrations; ionizing radiation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes / Occupational Exposure / Chromosome Aberrations / Promoter Regions, Genetic / Radiation Exposure / DNA Methylation / Epigenesis, Genetic Limits: Aged / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Bull Exp Biol Med Year: 2021 Document type: Article Affiliation country: RUSSIA Country of publication: United States

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