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Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial.
Chow, Clara K; Atkins, Emily R; Hillis, Graham S; Nelson, Mark R; Reid, Christopher M; Schlaich, Markus P; Hay, Peter; Rogers, Kris; Billot, Laurent; Burke, Michael; Chalmers, John; Neal, Bruce; Patel, Anushka; Usherwood, Tim; Webster, Ruth; Rodgers, Anthony.
Affiliation
  • Chow CK; Westmead Applied Research Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia. Electronic address: clara.chow@sydney.edu.au.
  • Atkins ER; Westmead Applied Research Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; The George Institute for Global Health, UNSW, Sydney, NSW, Australia.
  • Hillis GS; Royal Perth Hospital and Medical School, University of Western Australia, Perth, WA, Australia.
  • Nelson MR; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.
  • Reid CM; School of Public Health & Preventive Medicine Monash University, Melbourne, VIC, Australia; School of Population Health, Curtin University, Perth, WA, Australia.
  • Schlaich MP; Dobney Hypertension Centre, Royal Perth Hospital Research Foundation, Medical School, University of Western Australia, Perth, WA, Australia.
  • Hay P; Castle Hill Medical Centre, Sydney, NSW, Australia.
  • Rogers K; The George Institute for Global Health, UNSW, Sydney, NSW, Australia; Graduate School of Health, University of Technology Sydney, Sydney, NSW, Australia.
  • Billot L; The George Institute for Global Health, UNSW, Sydney, NSW, Australia.
  • Burke M; School of Medicine, Western Sydney University, Sydney, Australia.
  • Chalmers J; The George Institute for Global Health, UNSW, Sydney, NSW, Australia.
  • Neal B; The George Institute for Global Health, UNSW, Sydney, NSW, Australia; School of Public Health, Imperial College London, London, UK.
  • Patel A; The George Institute for Global Health, UNSW, Sydney, NSW, Australia.
  • Usherwood T; Westmead Applied Research Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; The George Institute for Global Health, UNSW, Sydney, NSW, Australia.
  • Webster R; The George Institute for Global Health, UNSW, Sydney, NSW, Australia; Centre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, NSW, Australia.
  • Rodgers A; The George Institute for Global Health, UNSW, Sydney, NSW, Australia.
Lancet ; 398(10305): 1043-1052, 2021 09 18.
Article in En | MEDLINE | ID: mdl-34469767
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Pressure / Bisoprolol / Amlodipine / Drug Therapy, Combination / Irbesartan / Hypertension / Indapamide / Antihypertensive Agents Type of study: Clinical_trials / Etiology_studies Limits: Female / Humans / Male / Middle aged Country/Region as subject: Oceania Language: En Journal: Lancet Year: 2021 Document type: Article Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Pressure / Bisoprolol / Amlodipine / Drug Therapy, Combination / Irbesartan / Hypertension / Indapamide / Antihypertensive Agents Type of study: Clinical_trials / Etiology_studies Limits: Female / Humans / Male / Middle aged Country/Region as subject: Oceania Language: En Journal: Lancet Year: 2021 Document type: Article Country of publication: United kingdom