ABCD, AmB colloidal dispersion; AIDS, acquired immunodeficiency syndrome; AP, antisolvent precipitation; ARDS, acute respiratory distress syndrome; AmB, amphotericin B; AmB-GCPQ, AmB-encapsulated N-palmitoyl-N-methyl-N,N-dimethyl-N,N,N-trimethyl-6-O-glycol-chitosan nanoparticles; AmB-IONP, AmB-loaded iron oxide nanoparticles; AmB-PM, AmB-polymeric micelles; AmB-SD, AmB sodium deoxycholate; AmBd, AmB deoxycholate; Amphotericin B; Aspergillus fumigatus, A. fumigatus; BBB, blood‒brain barrier; BCS, biopharmaceutics classification system; BDDE, butanediol diglycidyl ether; BSA, bovine serum albumin; BUN, blood urea nitrogen; C. Albicans, Candida Albicans; CFU, colony-forming unit; CLSM, confocal laser scanning microscope; CMC, carboxymethylated l-carrageenan; CP, chitosan-polyethylenimine; CS, chitosan; Conjugates; DDS, drug delivery systems; DMPC, dimyristoyl phosphatidyl choline; DMPG, dimyristoyl phosphatidylglycerole; DMSA, dimercaptosuccinic acid; Drug delivery; GNPs, gelatin nanoparticles; HPH, high-pressure homogenization; HPMC, hydroxypropyl methylcellulose; ICV, intensive care unit; IFIs, invasive fungal infections; Invasive fungal infections; L-AmB, liposomal AmB; LNA, linolenic acid; MAA, methacrylic acid; MFC, minimum fungicidal concentrations; MIC, minimum inhibitory concentration; MN, microneedles; MOP, microneedle ocular patch; MPEG-PCL, monomethoxy poly(ethylene glycol)-poly(epsilon-caprolactone); NEs, nanoemulsions; NLC, nanostructured lipid carriers; NPs, nanoparticles; Nanoparticles; P-407, poloxamer-407; PAM, polyacrylamide; PCL, polycaprolactone; PDA, poly(glycolic acid); PDLLA, poly(d,l-lactic acid); PDLLGA, poly(d,l-lactic-co-glycolic acid); PEG, poly(ethylene glycol); PEG-DSPE, PEG-lipid poly(ethylene glycol)-distearoylphosphatidylethanolamine; PEG-PBC, phenylboronic acid-functionalized polycarbonate/PEG; PEG-PUC, urea-functionalized polycarbonate/PEG; PGA-PPA, poly(l-lysine-b-l-phenylalanine) and poly(l-glutamic acid-b-l-phenylalanine); PLA, poly(lactic acid); PLGA, polyvinyl alcohol poly(lactic-co-glycolic acid); PLGA-PLH-PEG, PLGA-b-poly(l-histidine)-b-poly(ethylene glycol); PMMA, poly(methyl methacrylate); POR, porphyran; PVA, poly(vinyl alcohol); PVP, polyvinylpyrrolidone; Poor water-solubility; RBCs, red blood cells; RES, reticuloendothelial system; ROS, reactive oxygen species; SEM, scanning electron microscope; SL-AmB, sophorolipid-AmB; SLNs, solid lipid nanoparticles; Topical administration; Toxicity; γ-CD, γ-cyclodextrin; γ-PGA, γ-poly(gamma-glutamic acid