PEDF relieves kidney injury in type 2 diabetic nephropathy mice by reducing macrophage infiltration.

Li, Li; Zhang, Lan; Chen, Danyan; Yu, Keping; Gan, Hua; Yang, Gangyi

Li, Li; Zhang, Lan; Chen, Danyan; Yu, Keping; Gan, Hua; Yang, Gangyi.

Affiliation

Li L; Department of Endocrinology, Chongqing General Hospital, Chongqing, China. Inter20102020@163.com.
Zhang L; Department of Endocrinology, Chongqing General Hospital, Chongqing, China.
Chen D; Department of Endocrinology, Chongqing General Hospital, Chongqing, China.
Yu K; Department of Endocrinology, Chongqing General Hospital, Chongqing, China.
Gan H; The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yang G; Department of Endocrinology, Chongqing General Hospital, Chongqing, China.

Endokrynol Pol ; 72(6): 643-651, 2021.

Article in En | MEDLINE | ID: mdl-34647607

Subject(s)

Acute Kidney Injury/drug therapy; Diabetes Mellitus, Experimental/complications; Diabetes Mellitus, Type 2/complications; Diabetic Nephropathies/drug therapy; Eye Proteins/therapeutic use; Macrophages/drug effects; Nerve Growth Factors/therapeutic use; Serpins/therapeutic use; Animals; Creatinine; Diabetes Mellitus, Experimental/drug therapy; Diabetes Mellitus, Type 2/drug therapy; Mice; Peptides; Toll-Like Receptor 4

Key words

kidney injury; macrophage infiltration; pigment epithelium-derived factor; type 2 diabetes mellitus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serpins / Diabetes Mellitus, Experimental / Diabetes Mellitus, Type 2 / Diabetic Nephropathies / Eye Proteins / Acute Kidney Injury / Macrophages / Nerve Growth Factors Limits: Animals Language: En Journal: Endokrynol Pol Year: 2021 Document type: Article Affiliation country: China Country of publication: Poland

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