Atrial Cardiomyopathy: Pathophysiology and Clinical Consequences.
Cells
; 10(10)2021 09 30.
Article
in En
| MEDLINE
| ID: mdl-34685585
Around the world there are 33.5 million patients suffering from atrial fibrillation (AF) with an annual increase of 5 million cases. Most AF patients have an established form of an atrial cardiomyopathy. The concept of atrial cardiomyopathy was introduced in 2016. Thus, therapy of underlying diseases and atrial tissue changes appear as a cornerstone of AF therapy. Furthermore, therapy or prevention of atrial endocardial changes has the potential to reduce atrial thrombogenesis and thereby cerebral stroke. The present manuscript will summarize the underlying pathophysiology and remodeling processes observed in the development of an atrial cardiomyopathy, thrombogenesis, and atrial fibrillation. In particular, the impact of oxidative stress, inflammation, diabetes, and obesity will be addressed.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Atrial Fibrillation
/
Atrial Remodeling
/
Heart Atria
/
Cardiomyopathies
Limits:
Humans
Language:
En
Journal:
Cells
Year:
2021
Document type:
Article
Affiliation country:
Germany
Country of publication:
Switzerland