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Hemodynamic Alteration in the Liver in Acute Hepatitis: A Quantitative Evaluation Using Computed Tomographic Perfusion.
Nishie, Akihiro; Ushijima, Yasuhiro; Takayama, Yukihisa; Fujita, Nobuhiro; Kubo, Yuichiro; Ishimatsu, Keisuke; Tsurumaru, Daisuke; Kohjima, Motoyuki; Ishigami, Kousei.
Affiliation
  • Nishie A; Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan; nishie_a@med.u-ryukyu.ac.jp.
  • Ushijima Y; Department of Advanced Imaging and Interventional Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Takayama Y; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Fujita N; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Kubo Y; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Ishimatsu K; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Tsurumaru D; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Kohjima M; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Ishigami K; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
In Vivo ; 35(6): 3537-3545, 2021.
Article in En | MEDLINE | ID: mdl-34697192
BACKGROUND/AIM: We aimed to elucidate the hemodynamic alterations in the liver of patients with acute hepatitis (AH) using computed tomography perfusion imaging. PATIENTS AND METHODS: For 14 patients with AH and nine patients with no disease (ND group), we compared the mean arterial blood flow (AF), portal blood flow (PF) and perfusion index (%) [PI=AF/(AF+PF) ×100] of the right and left liver lobes and investigated their relationship with clinical factors. RESULTS: The mean PI of the right lobe in the AH group (30.5±10.0%) was significantly higher than that in the ND group (20.8±9.7%) (p=0.031). For all patients of the AH and ND groups, the PI of the right lobe was increased as the prothrombin time decreased (R=-0.56, p=0.006) and as the prothrombin time-international normalized ratio increased (R=0.48, p=0.02). CONCLUSION: The PI of the right liver lobe may increase in AH and may be a predictive parameter for the severity of hepatic failure.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis / Liver Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: In Vivo Journal subject: NEOPLASIAS Year: 2021 Document type: Article Country of publication: Greece
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis / Liver Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: In Vivo Journal subject: NEOPLASIAS Year: 2021 Document type: Article Country of publication: Greece