Polymorphism rs2682818 participates in the progression of colorectal carcinoma via miR-618-TIMP1 regulatory axis.

Shao, Wei; Xia, Haina; Lan, Qiangfang; Gu, Jialu; Huang, Haidong; Zheng, Fei; Zheng, Youyou

Shao, Wei; Xia, Haina; Lan, Qiangfang; Gu, Jialu; Huang, Haidong; Zheng, Fei; Zheng, Youyou.

Affiliation

Shao W; Zhoushan Putuo District People's Hospital, Zhoushan, 316100, China. shaowei_putuo01@126.com.
Xia H; Zhoushan Putuo District People's Hospital, Zhoushan, 316100, China.
Lan Q; Zhoushan Putuo District People's Hospital, Zhoushan, 316100, China.
Gu J; Zhoushan Putuo District People's Hospital, Zhoushan, 316100, China.
Huang H; Zhoushan Putuo District People's Hospital, Zhoushan, 316100, China.
Zheng F; Zhoushan Putuo District People's Hospital, Zhoushan, 316100, China.
Zheng Y; Zhoushan Putuo District People's Hospital, Zhoushan, 316100, China.

Sci Rep ; 11(1): 23186, 2021 11 30.

Article in En | MEDLINE | ID: mdl-34848810

Subject(s)

Colorectal Neoplasms/genetics; Gene Expression Regulation, Neoplastic; MicroRNAs/genetics; Polymorphism, Single Nucleotide; Tissue Inhibitor of Metalloproteinase-1/genetics; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms/mortality; Computational Biology/methods; Disease Progression; Female; Genetic Predisposition to Disease; Genotype; HCT116 Cells; HEK293 Cells; Heterozygote; Homozygote; Humans; Kaplan-Meier Estimate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Phenotype; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Gene Expression Regulation, Neoplastic / Tissue Inhibitor of Metalloproteinase-1 / Polymorphism, Single Nucleotide / MicroRNAs Limits: Animals / Female / Humans Language: En Journal: Sci Rep Year: 2021 Document type: Article Affiliation country: China Country of publication: United kingdom

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