Evaluation of Cellular Targeting by Fab' vs Full-Length Antibodies in Antibody-Nanoparticle Conjugates (ANCs) Using CD4 T-cells.

Singh, Khushboo; Canakci, Mine; Kanjilal, Pintu; Williams, Natalie; Shanthalingam, Sudarvili; Osborne, Barbara A; Thayumanavan, S

Singh, Khushboo; Canakci, Mine; Kanjilal, Pintu; Williams, Natalie; Shanthalingam, Sudarvili; Osborne, Barbara A; Thayumanavan, S.

Affiliation

Singh K; Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.
Canakci M; Center for Bioactive Delivery, Institute for Applied Life Sciences University of Massachusetts, Amherst, Amherst, Massachusetts 01003, United States.
Kanjilal P; Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.
Williams N; Department of Veterinary and Animal Sciences, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.
Shanthalingam S; Molecular and Cellular Biology Program, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.
Osborne BA; Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.
Thayumanavan S; Center for Bioactive Delivery, Institute for Applied Life Sciences University of Massachusetts, Amherst, Amherst, Massachusetts 01003, United States.

Bioconjug Chem ; 33(3): 486-495, 2022 03 16.

Article in En | MEDLINE | ID: mdl-35139308

Subject(s)

Immunoconjugates; Nanoparticles; Antibodies, Monoclonal; CD4-Positive T-Lymphocytes; Immunoglobulin Fab Fragments

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoconjugates / Nanoparticles Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States

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