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Safe Renal Transplantation to the Extraperitoneal Cavity in Children Weighing Less Than 15 kg.
Hata, Keisuke; Ishida, Hideki; Ishizuka, Kiyonobu; Unagami, Kohei; Kanzawa, Taichi; Omoto, Kazuya; Shimizu, Tomokazu; Miura, Kenichiro; Hattori, Motoshi; Tanabe, Kazunari.
Affiliation
  • Hata K; Department of Urology, Tokyo Women's Medical University, Tokyo. Electronic address: hata.keisuke@twmu.ac.jp.
  • Ishida H; Department of Urology, Tokyo Women's Medical University, Tokyo; Department of Organ Transplant Medicine, Tokyo Women's Medical University, Tokyo.
  • Ishizuka K; Department of Pediatric Nephrology, Tokyo Women's Medical University, Tokyo, Japan.
  • Unagami K; Department of Organ Transplant Medicine, Tokyo Women's Medical University, Tokyo.
  • Kanzawa T; Department of Urology, Tokyo Women's Medical University, Tokyo.
  • Omoto K; Department of Urology, Tokyo Women's Medical University, Tokyo.
  • Shimizu T; Department of Urology, Tokyo Women's Medical University, Tokyo.
  • Miura K; Department of Pediatric Nephrology, Tokyo Women's Medical University, Tokyo, Japan.
  • Hattori M; Department of Pediatric Nephrology, Tokyo Women's Medical University, Tokyo, Japan.
  • Tanabe K; Department of Urology, Tokyo Women's Medical University, Tokyo.
Transplant Proc ; 54(2): 248-253, 2022 Mar.
Article in En | MEDLINE | ID: mdl-35151494
Pediatric renal transplantation is associated with various surgical complications due to the complexity of the technique and the often-fragile condition of patients with end-stage renal disease. We evaluated the surgical complications associated with renal transplantation via the extraperitoneal approach in pediatric recipients. This retrospective study enrolled 280 patients younger than 16 years old who underwent renal transplantation via the extraperitoneal approach: 216 patients underwent transplant placement in the iliac fossa like in adults, and 64 underwent transplant placement in the distal part of the original renal lower pole (the extraperitoneal cavity). On the basis of the Clavien-Dindo classification, 30 patients (10.7%) showed grade 2 complications and 12 patients (4.3%) showed grade 3 or higher complications. None of the patients showed gastrointestinal complications. In a Cox regression analysis, grade 2 or higher complications were significantly associated with weight less than 15 kg (P = .027) and operative times longer than 245 minutes (P = .029). Among the 49 patients weighing less than 15 kg with an allograft placed in a distal portion of the original renal lower pole, only 3 patients (6.1%) developed surgical complications. Thus, allograft placement in the extraperitoneal cavity can be performed safely in children weighing less than 15 kg.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Kidney Transplantation / Kidney Failure, Chronic Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Humans Language: En Journal: Transplant Proc Year: 2022 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Kidney Transplantation / Kidney Failure, Chronic Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Humans Language: En Journal: Transplant Proc Year: 2022 Document type: Article Country of publication: United States