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Pediatric Osteosarcoma: Pearls and Pitfalls.
Menendez, Nelson; Epelman, Monica; Shao, Lei; Douglas, Dorothea; Meyers, Arthur B.
Affiliation
  • Menendez N; University of Central Florida College of Medicine, Orlando, FL; Department of Radiology, Nemours Children's Health System/Nemours Children's Hospital, Orlando, FL.
  • Epelman M; University of Central Florida College of Medicine, Orlando, FL; Department of Radiology, Nemours Children's Health System/Nemours Children's Hospital, Orlando, FL.
  • Shao L; University of Central Florida College of Medicine, Orlando, FL; Department of Pathology and Lab Medicine, Nemours Children's Health System/Nemours Children's Hospital, Orlando, FL.
  • Douglas D; University of Central Florida College of Medicine, Orlando, FL; Department of Pediatrics, Nemours Children's Health System/Nemours Children's Hospital, Orlando, FL.
  • Meyers AB; Department of Radiology, Cincinnati Children's Hospital Medical Center, Dept. of Radiology, Cincinnati, OH. Electronic address: arthur.meyers@cchmc.org.
Semin Ultrasound CT MR ; 43(1): 97-114, 2022 Feb.
Article in En | MEDLINE | ID: mdl-35164914
Osteosarcoma is a malignant bone tumor most commonly presenting in children. It has a bimodal distribution with a peak incidence occurring during the ages of 10-14 years old and in adults greater than age 65. The first peak of osteosarcoma correlates with the increased proliferation of bone during the pubertal growth period. Osteosarcoma most frequently presents with localized bone pain, swelling, and an antalgic gait. The patient may attribute symptoms to trauma or strenuous exercise, causing the patient to be managed conservatively. In these cases, the pain persists and eventually leads to further evaluation. The most common type of osteosarcoma is the conventional high-grade osteosarcoma. For conventional osteosarcoma, the diagnosis is typically made or strongly suggested based upon the initial radiographic appearance. Other types of osteosarcomas include low grade central, telangiectatic, small-cell, surface and intracortical. Consequently, it is important for radiologists to be aware of these subtypes and the imaging features that differentiate them from other etiologies to prevent a delay in treatment.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / Osteosarcoma Limits: Adolescent / Aged / Child / Humans Language: En Journal: Semin Ultrasound CT MR Journal subject: DIAGNOSTICO POR IMAGEM Year: 2022 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / Osteosarcoma Limits: Adolescent / Aged / Child / Humans Language: En Journal: Semin Ultrasound CT MR Journal subject: DIAGNOSTICO POR IMAGEM Year: 2022 Document type: Article Country of publication: United States