Post-marketing surveillance of carfilzomib in Japanese patients with relapsed or refractory multiple myeloma.
Future Oncol
; 18(24): 2661-2674, 2022 Aug.
Article
in En
| MEDLINE
| ID: mdl-35815645
Carfilzomib is a medicine that was recently approved for the treatment of cancer of bone marrow (multiple myeloma) that comes back or does not respond to previous treatment (relapsed or refractory). Data gathered from the hospitals, where the medicine is commonly used, was used to generate evidence. We looked at how well carfilzomib works in Japanese participants and if it is safe. Overall, 63.5% of participants treated with carfilzomib had side effects and 37.7% had serious side effects. Death occurred in 3.1% of participants during the study. Decrease in bone marrow and blood cells, infections, heart and kidney disorder, liver failure or dysfunction, and high blood pressure occurred in 5% or more participants. In 46.5% of participants the tumors had disappeared or shrank. In Japanese participants, carfilzomib was found to be safe and effective treatment for cancer of bone marrow that comes back or does not respond to previous treatment.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Multiple Myeloma
Type of study:
Screening_studies
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Future Oncol
Year:
2022
Document type:
Article
Affiliation country:
Japan
Country of publication:
United kingdom