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Schisandrol B protects against cholestatic liver injury by inhibiting pyroptosis through pregnane X receptor.
Liang, Hangfei; Yang, Xiao; Li, Huilin; Wang, Xinhui; Su, Haiguo; Li, Xuan; Tian, Jianing; Cai, Chenghui; Huang, Min; Bi, Huichang.
Affiliation
  • Liang H; Guandong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
  • Yang X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
  • Li H; Guandong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
  • Wang X; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, China.
  • Su H; Guandong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
  • Li X; Guandong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
  • Tian J; Guandong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
  • Cai C; Guandong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
  • Huang M; Guandong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China. Electronic address: huangmin@mail.sysu.edu.cn.
  • Bi H; Guandong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmac
Biochem Pharmacol ; 204: 115222, 2022 10.
Article in En | MEDLINE | ID: mdl-35988735
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholestasis / Pyroptosis Limits: Humans Language: En Journal: Biochem Pharmacol Year: 2022 Document type: Article Affiliation country: China Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholestasis / Pyroptosis Limits: Humans Language: En Journal: Biochem Pharmacol Year: 2022 Document type: Article Affiliation country: China Country of publication: United kingdom