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[Influencing factors of nutritional status and change in 50 patients with oral squamous cell carcinoma during treatment].
Maierhaba, Maihemuti; Bai, Jie; Rusitanmu, Yimiti; Yao, Zhi-Tao.
Affiliation
  • Maierhaba M; Department of Orthognathic Surgery for Maxillofacial Trauma, First Affiliated Hospital and Stomatological Hospital of Xinjiang Medical University. Urumqi 830054, China. E-mail: 874176691@qq.com.
Shanghai Kou Qiang Yi Xue ; 31(2): 205-210, 2022 Apr.
Article in Zh | MEDLINE | ID: mdl-36110082
PURPOSE: To investigate the changes of nutritional status in patients with oral squamous cell carcinoma(OSCC) and analyze the influencing factors during treatment. METHODS: Anthropometry (weight, BMI, waistline, middle circumference of left and right upper arms) and laboratory index(serum prealbumin, serum albumin, transferrins, 25-hydroxyvitamin D) were measured to represent the nutritional status of 50 patients with OSCC before operation, two days, one month and three months after operation. SPSS 24.0 software package was used for statistical analysis of the data, and influencing factors of nutrition risk in OSCC patient were analyzed with binary logistic regression model. RESULTS: Univariate and multivariate analysis showed that advanced age(OR=1.127,95%CI: 1.053-1.207), low educational level (OR=5.250, 95%CI: 1.147-21.796), smoking(OR=6.182, 95%CI: 1.631-23.433), alcohol use(OR=5.227, 95%CI: 1.336-20.450), chemoradiotherapy (OR=3.984, 95%CI: 1.199-13.242), free flap surgery (OR=8.000, 95%CI: 2.060-31.068), tracheostomy(OR=3.960, 95%CI: 1.069-14.671), cervical lymph node metastasis(OR=4.821, 95%CI: 1.418-16.399), buccal carcinoma(OR=9.000, 95%CI:1.140-71.038), tongue cancer(OR=7.200, 95%CI: 1.081-47.962), tumor stage T3-4(OR=3.542, 95%CI: 1.066-11.771) were independent influencing factors of the nutritional status of patients with OSCC. CONCLUSIONS: Aging, low educational level, smoking history and drinking history in the general demographic characteristics of patients, and chemoradiotherapy, free flap surgery, tracheostomy during treatment, as well as buccal carcinoma, tongue cancer, advanced stage and cervical lymph node metastasis are clinical characteristics, which affect the nutrition level during the treatment for OSCC patients.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Mouth Neoplasms / Tongue Neoplasms / Squamous Cell Carcinoma of Head and Neck Type of study: Prognostic_studies Limits: Humans Language: Zh Journal: Shanghai Kou Qiang Yi Xue Journal subject: ODONTOLOGIA Year: 2022 Document type: Article Country of publication: China
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Collection: 01-internacional Database: MEDLINE Main subject: Mouth Neoplasms / Tongue Neoplasms / Squamous Cell Carcinoma of Head and Neck Type of study: Prognostic_studies Limits: Humans Language: Zh Journal: Shanghai Kou Qiang Yi Xue Journal subject: ODONTOLOGIA Year: 2022 Document type: Article Country of publication: China