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Novel mechanism of napabucasin, a naturally derived furanonaphthoquinone: apoptosis and autophagy induction in lung cancer cells through direct targeting on Akt/mTOR proteins.
Petsri, Korrakod; Thongsom, Sunisa; Racha, Satapat; Chamni, Supakarn; Jindapol, Saresa; Kaekratoke, Nantawat; Zou, Hongbin; Chanvorachote, Pithi.
Affiliation
  • Petsri K; Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Thongsom S; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Racha S; Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Chamni S; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Jindapol S; Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Kaekratoke N; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Zou H; Interdisciplinary Program in Pharmacology, Graduate School, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Chanvorachote P; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
BMC Complement Med Ther ; 22(1): 250, 2022 Sep 30.
Article in En | MEDLINE | ID: mdl-36180880
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins c-akt / Lung Neoplasms Limits: Humans Language: En Journal: BMC Complement Med Ther Year: 2022 Document type: Article Affiliation country: Thailand Country of publication: United kingdom
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins c-akt / Lung Neoplasms Limits: Humans Language: En Journal: BMC Complement Med Ther Year: 2022 Document type: Article Affiliation country: Thailand Country of publication: United kingdom