The CCL2 rs4586 SNP Is Associated with Slower Amyloid-ß Deposition and Faster Tau Accumulation of Alzheimer's Disease.

Gao, Fan; Zhang, Peng-Fei; Gao, Jing; Song, Jinghui; Chi, Song

Gao, Fan; Zhang, Peng-Fei; Gao, Jing; Song, Jinghui; Chi, Song.

Affiliation

Gao F; Department of Neurology, the Affiliated Hospital of Qingdao University, Qingdao, China.
Zhang PF; Department of Medicine, Hangzhou Juno Genomics Inc, Hangzhou, China.
Gao J; Department of Neurology, the Affiliated Hospital of Qingdao University, Qingdao, China.
Song J; Department of Neurology, the Affiliated Hospital of Qingdao University, Qingdao, China.
Chi S; Department of Neurology, the Affiliated Hospital of Qingdao University, Qingdao, China.

J Alzheimers Dis ; 90(4): 1647-1657, 2022.

Article in En | MEDLINE | ID: mdl-36314210

Subject(s)

Alzheimer Disease; Cognitive Dysfunction; Humans; Alzheimer Disease/diagnostic imaging; Alzheimer Disease/genetics; Alzheimer Disease/cerebrospinal fluid; Ligands; Polymorphism, Single Nucleotide/genetics; tau Proteins/cerebrospinal fluid; Amyloid beta-Peptides/cerebrospinal fluid; Cognitive Dysfunction/cerebrospinal fluid; Positron-Emission Tomography/methods; Biomarkers/cerebrospinal fluid; Chemokines; Chemokine CCL2/genetics

Key words

Alzheimer's Disease Neuroimaging Initiative; Alzheimer's disease; CCL2; amyloid-ß; tau

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease / Cognitive Dysfunction Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2022 Document type: Article Affiliation country: China Country of publication: Netherlands

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