Asiatic Acid Fabricated Nanoconstructs to Mitigate Amyloid Beta<sub>1-42</sub> Induced Injury in SH-SY5Y Cells In-Vitro and Ameliorates Cognitive Impairment by Dual Cholinesterase Inhibition and Attenuation of Oxidative Stress In-Vivo.

Halder, Tripti; Patel, Bharat; Acharya, Niyati

Asiatic Acid Fabricated Nanoconstructs to Mitigate Amyloid Beta_1-42 Induced Injury in SH-SY5Y Cells In-Vitro and Ameliorates Cognitive Impairment by Dual Cholinesterase Inhibition and Attenuation of Oxidative Stress In-Vivo.

Halder, Tripti; Patel, Bharat; Acharya, Niyati.

Affiliation

Halder T; Department of Pharmacognosy, Institute of Pharmacy, Nirma University, Ahmedabad, 382481, Gujarat, India.
Patel B; Department of Pharmacognosy, Institute of Pharmacy, Nirma University, Ahmedabad, 382481, Gujarat, India.
Acharya N; Department of Pharmacognosy, Institute of Pharmacy, Nirma University, Ahmedabad, 382481, Gujarat, India. niyati.acharya@nirmauni.ac.in.

Pharm Res ; 40(1): 197-213, 2023 Jan.

Article in En | MEDLINE | ID: mdl-36376605

Subject(s)

Alzheimer Disease; Cognitive Dysfunction; Neuroblastoma; Neuroprotective Agents; Humans; Rats; Animals; Amyloid beta-Peptides/metabolism; Neuroblastoma/drug therapy; Alzheimer Disease/drug therapy; Alzheimer Disease/pathology; Cognitive Dysfunction/drug therapy; Cognitive Dysfunction/pathology; Oxidative Stress; Cholinesterases; Neuroprotective Agents/pharmacology

Key words

alzheimer's disease; amyloid beta; asiatic acid; nanostructured lipid carriers; thioflavin

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neuroprotective Agents / Alzheimer Disease / Cognitive Dysfunction / Neuroblastoma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Pharm Res Year: 2023 Document type: Article Affiliation country: India Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google