A robust and efficient alluvial filtration method for the clarification of adeno-associated viruses from crude cell lysates.

Meierrieks, Frederik; Pickl, Andreas; Wolff, Michael W

Meierrieks, Frederik; Pickl, Andreas; Wolff, Michael W.

Affiliation

Meierrieks F; Lab Essentials Applications Development, Sartorius Lab Instruments GmbH & Co. KG, Otto-Brenner-Straße 20, 37079 Goettingen, Germany.
Pickl A; Lab Essentials Applications Development, Sartorius Lab Instruments GmbH & Co. KG, Otto-Brenner-Straße 20, 37079 Goettingen, Germany. Electronic address: Andreas.Pickl@Sartorius.com.
Wolff MW; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Giessen, Germany; Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Giessen, Germany. Electronic address: Michael.Wolff@lse.thm.de.

J Biotechnol ; 367: 31-41, 2023 Apr 10.

Article in En | MEDLINE | ID: mdl-36997072

Subject(s)

Dependovirus; Genetic Vectors; Dependovirus/genetics; DNA; Serogroup

Key words

Adeno-associated virus; Clarification; Diatomaceous earth; Downstream processing; Filtration

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dependovirus / Genetic Vectors Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: J Biotechnol Journal subject: BIOTECNOLOGIA Year: 2023 Document type: Article Affiliation country: Germany Country of publication: Netherlands

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