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Novel mRNA Signature for Anti-TNF-α Therapy Primary Response in Patients With Ulcerative Colitis.
Yang, Xinhui; Shi, Jintong; Wang, Gaoyang; Chen, Huifang; Ye, Youqiong; Zhong, Jie; Wang, Zhengting.
Affiliation
  • Yang X; Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P.R. China.
  • Shi J; Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P.R. China.
  • Wang G; Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P.R. China.
  • Chen H; Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P.R. China.
  • Ye Y; Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P.R. China.
  • Zhong J; Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P.R. China.
  • Wang Z; Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P.R. China.
Inflamm Bowel Dis ; 29(9): 1458-1469, 2023 09 01.
Article in En | MEDLINE | ID: mdl-37080716
We developed a de novo response-associated transcription signature score (logOR_Score) to predict the response of patients with UC to anti-TNF-α agents prior to treatment and explored the different response mechanisms of UC.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative Type of study: Prognostic_studies Limits: Humans Language: En Journal: Inflamm Bowel Dis Journal subject: GASTROENTEROLOGIA Year: 2023 Document type: Article Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative Type of study: Prognostic_studies Limits: Humans Language: En Journal: Inflamm Bowel Dis Journal subject: GASTROENTEROLOGIA Year: 2023 Document type: Article Country of publication: United kingdom