Polysaccharides from sea buckthorn (Hippophae rhamnoides L.) berries ameliorate cognitive dysfunction in AD mice induced by a combination of d-gal and AlCl<sub>3</sub> by suppressing oxidative stress and inflammation reaction.

Zhao, Hong; Liu, Jiayue; Wang, Yanyan; Shao, Mengting; Wang, Lihong; Tang, Weiwei; Wang, Yuliang; Li, Xiaoliang

Polysaccharides from sea buckthorn (Hippophae rhamnoides L.) berries ameliorate cognitive dysfunction in AD mice induced by a combination of d-gal and AlCl₃ by suppressing oxidative stress and inflammation reaction.

Zhao, Hong; Liu, Jiayue; Wang, Yanyan; Shao, Mengting; Wang, Lihong; Tang, Weiwei; Wang, Yuliang; Li, Xiaoliang.

Affiliation

Zhao H; College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, People's Republic of China.
Liu J; College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, People's Republic of China.
Wang Y; College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, People's Republic of China.
Shao M; College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, People's Republic of China.
Wang L; College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, People's Republic of China.
Tang W; College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, People's Republic of China.
Wang Y; College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, People's Republic of China.
Li X; Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Provincial, Key Laboratory for Research and Development of Tropical Herbs, Haikou Key Laboratory of Li Nationality Medicine, School of Pharmacy, Hainan Medical University, Haikou, People's Republic of China.

J Sci Food Agric ; 103(12): 6005-6016, 2023 Sep.

Article in En | MEDLINE | ID: mdl-37132070

Subject(s)

Alzheimer Disease; Cognitive Dysfunction; Hippophae; Mice; Animals; Hippophae/chemistry; Alzheimer Disease/drug therapy; Toll-Like Receptor 4/genetics; Toll-Like Receptor 4/analysis; Toll-Like Receptor 4/metabolism; Kelch-Like ECH-Associated Protein 1/metabolism; Fruit/chemistry; NF-E2-Related Factor 2/genetics; NF-E2-Related Factor 2/metabolism; Myeloid Differentiation Factor 88/genetics; Myeloid Differentiation Factor 88/analysis; Myeloid Differentiation Factor 88/metabolism; Oxidative Stress; Inflammation/drug therapy; Polysaccharides/analysis; Cognitive Dysfunction/drug therapy

Key words

d-gal; AlCl3; Alzheimer's disease; polysaccharide; sea buckthorn

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hippophae / Alzheimer Disease / Cognitive Dysfunction Limits: Animals Language: En Journal: J Sci Food Agric Year: 2023 Document type: Article Country of publication: United kingdom

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