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CCL2 promotes lymphatic metastasis via activating RhoA and Rac1 pathway and predict prognosis to some extent in tongue cancer.
Dong, Yuqing; Zhang, Shuning; Zhao, Shuangyuan; Xuan, Ming; Zhu, Guiquan; Zhang, Zhuang; Guo, Weihua.
Affiliation
  • Dong Y; State Key Laboratory of Oral Disease & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
  • Zhang S; Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
  • Zhao S; State Key Laboratory of Oral Disease & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
  • Xuan M; Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
  • Zhu G; State Key Laboratory of Oral Disease & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
  • Zhang Z; Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
  • Guo W; State Key Laboratory of Oral Disease & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Cancer Biol Ther ; 24(1): 2205342, 2023 12 31.
Article in En | MEDLINE | ID: mdl-37132640
Increased CCL2 concentration is associated with short- term progress-free survival.CCL2 levels predict patient prognosis are similar to TNM staging.CCL2 levels may be a preferable biomarker for predicting the prognosis of patients with tongue cancer.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tongue Neoplasms / Proto-Oncogene Proteins c-akt Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Cancer Biol Ther Journal subject: NEOPLASIAS / TERAPEUTICA Year: 2023 Document type: Article Affiliation country: China Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tongue Neoplasms / Proto-Oncogene Proteins c-akt Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Cancer Biol Ther Journal subject: NEOPLASIAS / TERAPEUTICA Year: 2023 Document type: Article Affiliation country: China Country of publication: United States