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Case Series of Frontal Fibrosing Alopecia and Fibrosing Alopecia in a Pattern Distribution: Is There a Familial Correlation?
Gavazzoni Dias, Maria Fernanda Reis; Lofeu Cury, Amanda; Vilar, Enoi Aparecida Guedes; Peixoto, Patricia Guimarães; Ekelem, Chloe.
Affiliation
  • Gavazzoni Dias MFR; Department of Dermatology, Hospital Universitário Antônio Pedro, Niterói, Brazil.
  • Lofeu Cury A; Department of Dermatology, Hospital Universitário Antônio Pedro, Niterói, Brazil.
  • Vilar EAG; Department of Pathology, Hospital Universitário Antônio Pedro, Niterói, Brazil.
  • Peixoto PG; Clínica Patricia Guimarães - Medicina e Tricologia, Santa Efigênia, Belo Horizonte, Brazil.
  • Ekelem C; Department of Dermatology, University of Utah, Salt Lake City, Utah, USA.
Skin Appendage Disord ; 9(3): 230-234, 2023 Jun.
Article in En | MEDLINE | ID: mdl-37325284
Introduction: Frontal Fibrosing Alopecia (FFA) and Fibrosing Alopecia in a Pattern Distribution (FAPD) are two distinct entities of cicatricial pattern hair loss that share histological features of perifollicular lichenoid inflammation associated with concentric fibrosis. Although the pathophysiology of FFA and FAPD are still unknown, recently published reports of familial cases indicate a possible genetic correlation. Case Presentation: We report 6 cases of familial alopecia composed of mothers and daughters: five with FFA and one with FAPD. We describe clinical, trichoscopy and histological correlation in cases of familial alopecia. Conclusions: These cases of mother and daughter disease association suggest a potential benefit of and role for performing systematic scalp examinations of all first-degree relatives of patients with pattern cicatricial alopecia.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Skin Appendage Disord Year: 2023 Document type: Article Affiliation country: Brazil Country of publication: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Skin Appendage Disord Year: 2023 Document type: Article Affiliation country: Brazil Country of publication: Switzerland