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Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/ß.
Park, Jin-Hee; Hwang, Jeong-Woo; Lee, Hyun-Ju; Jang, Geum Mi; Jeong, Yoo Joo; Cho, Joonho; Seo, Jinsoo; Hoe, Hyang-Sook.
Affiliation
  • Park JH; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.
  • Hwang JW; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Republic of Korea.
  • Lee HJ; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.
  • Jang GM; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.
  • Jeong YJ; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Republic of Korea.
  • Cho J; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), Daegu, Republic of Korea.
  • Seo J; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Republic of Korea.
  • Hoe HS; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Republic of Korea.
Front Immunol ; 14: 1150940, 2023.
Article in En | MEDLINE | ID: mdl-37435081
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycogen Synthase Kinase 3 / Alzheimer Disease / NLR Family, Pyrin Domain-Containing 3 Protein Limits: Animals Language: En Journal: Front Immunol Year: 2023 Document type: Article Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycogen Synthase Kinase 3 / Alzheimer Disease / NLR Family, Pyrin Domain-Containing 3 Protein Limits: Animals Language: En Journal: Front Immunol Year: 2023 Document type: Article Country of publication: Switzerland