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Total and Free Blood and Plasma Concentration Changes in Pregnancy for Medicines Highly Bound to Plasma Proteins: Application of Physiologically Based Pharmacokinetic Modelling to Understand the Impact on Efficacy.
Coppola, Paola; Butler, Andrew; Cole, Susan; Kerwash, Essam.
Affiliation
  • Coppola P; Medicines and Healthcare Products Regulatory Agency (MHRA), 10 South Colonnade, London E14 4PU, UK.
  • Butler A; Medicines and Healthcare Products Regulatory Agency (MHRA), 10 South Colonnade, London E14 4PU, UK.
  • Cole S; Medicines and Healthcare Products Regulatory Agency (MHRA), 10 South Colonnade, London E14 4PU, UK.
  • Kerwash E; Medicines and Healthcare Products Regulatory Agency (MHRA), 10 South Colonnade, London E14 4PU, UK.
Pharmaceutics ; 15(10)2023 Oct 13.
Article in En | MEDLINE | ID: mdl-37896215
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Pharmaceutics Year: 2023 Document type: Article Affiliation country: United kingdom Country of publication: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Pharmaceutics Year: 2023 Document type: Article Affiliation country: United kingdom Country of publication: Switzerland