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Host-microbial crosstalk relies on "tuft" love.
De Santis, Stefania; Pizarro, Theresa T.
Affiliation
  • De Santis S; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
  • Pizarro TT; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA. Electronic address: theresa.pizarro@case.edu.
Immunity ; 57(2): 195-197, 2024 Feb 13.
Article in En | MEDLINE | ID: mdl-38354697
ABSTRACT
How commensals influence intestinal immunity is incompletely understood. In this issue of Immunity, Eshleman et al. demonstrate that microbiota-derived butyrate restrains tuft cell development via HDAC3 modulation in intestinal epithelial cells, showing how microbial metabolites impact intestinal type 2 immunity.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microbiota / Intestinal Mucosa Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2024 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microbiota / Intestinal Mucosa Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2024 Document type: Article Affiliation country: United States