Inhibition of human leukocyte elastase, cathepsin G, chymotrypsin A alpha, and porcine pancreatic elastase with substituted isobenzofuranones and benzopyrandiones.

Hemmi, K; Harper, J W; Powers, J C

Hemmi, K; Harper, J W; Powers, J C.

Biochemistry ; 24(8): 1841-8, 1985 Apr 09.

Article in En | MEDLINE | ID: mdl-3848330

Subject(s)

Benzofurans/pharmacology; Benzopyrans/pharmacology; Cathepsins/antagonists & inhibitors; Chymotrypsin/antagonists & inhibitors; Leukocytes/enzymology; Pancreatic Elastase/antagonists & inhibitors; Animals; Benzofurans/chemical synthesis; Benzopyrans/chemical synthesis; Cathepsin G; Humans; Indicators and Reagents; Kinetics; Pancreas/enzymology; Pancreatic Elastase/blood; Serine Endopeptidases; Structure-Activity Relationship; Swine

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Collection: 01-internacional Database: MEDLINE Main subject: Benzofurans / Benzopyrans / Chymotrypsin / Pancreatic Elastase / Cathepsins / Leukocytes Limits: Animals / Humans Language: En Journal: Biochemistry Year: 1985 Document type: Article

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