Emerging Role of Plasma Microbial Cell-free DNA in the Diagnosis of Pediatric Mucormycosis.
Pediatr Infect Dis J
; 43(7): 704-707, 2024 Jul 01.
Article
in En
| MEDLINE
| ID: mdl-38502901
ABSTRACT
Mucormycosis is a rare and devastating angioinvasive infection that can be challenging to diagnose due to the low sensitivity of current noninvasive diagnostics and the lack of a "gold standard" reference test. We describe a retrospective case series of children with suspected mucormycosis where plasma microbial cell-free DNA testing was utilized in the diagnostic evaluation to illustrate the ways in which microbial cell-free DNA testing can noninvasively contribute to the evaluation and management of at-risk, immunosuppressed patients suspected of mucormycosis.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
DNA, Fungal
/
Cell-Free Nucleic Acids
/
Mucormycosis
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Pediatr Infect Dis J
Journal subject:
DOENCAS TRANSMISSIVEIS
/
PEDIATRIA
Year:
2024
Document type:
Article
Country of publication:
United States