[Latest advances in the development of tuberculosis vaccines in global clinical trials: a review].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
; 36(2): 201-206, 2024 Mar 29.
Article
in Zh
| MEDLINE
| ID: mdl-38857967
ABSTRACT
Tuberculosis (TB) remains one of the biggest infectious killers worldwide. Vaccine is the most satisfactory tool for prevention of TB; however, Bacillus Calmette-Guérin (BCG), the widely used vaccine in clinical for the prevention of TB, has limitations in protective effects. Development of novel TB vaccines is therefore of urgent need. Currently, there are 15 novel TB vaccine candidates in clinical trials, including live-attenuated vaccines, inactivated vaccines, subunit vaccines and viral-vectored vaccines, which open the door for the ultimate target of the End TB Strategy. This review summarizes the latest advances in the development of TB vaccines in global clinical trials, so as to provide insights into TB control.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tuberculosis
/
Clinical Trials as Topic
/
Tuberculosis Vaccines
Limits:
Humans
Language:
Zh
Journal:
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
China