Multidrug-resistant bacterial infections in the liver transplant setting.
Updates Surg
; 2024 Jun 25.
Article
in En
| MEDLINE
| ID: mdl-38918314
ABSTRACT
Bacterial infections pose a life-threatening complication in patients with decompensated liver cirrhosis and acute-on-chronic liver failure. An increasing prevalence of infections caused by multidrug-resistant organisms (MDROs) has been observed in these patients, significantly impacting prognosis. A growing body of evidence has identified the most common risk factors for such infections, enabling the development of preventive strategies and therapeutic interventions. MDRO infections may also occur after liver transplantation (most commonly in the early post-operative phase), affecting both graft and patient survival. This review provides an overview of MDRO infections before and after liver transplantation, discussing epidemiological aspects, risk factors, prevention strategies, and novel therapeutic approaches. Furthermore, it examines the implications of MDRO infections in the context of prioritizing liver transplantation for the most severe patients, such as those with acute-on-chronic liver failure.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Updates Surg
Year:
2024
Document type:
Article
Affiliation country:
Italy
Country of publication:
Italy