Cutaneous mucormycosis infection owing to Rhizomucor variabilis presenting as recurrent lower limb ulceration and cellulitis in a diabetic patient.
Dermatol Online J
; 30(2)2024 Apr 15.
Article
in En
| MEDLINE
| ID: mdl-38959919
ABSTRACT
Primary cutaneous mucormycosis is caused by environmental fungi and may complicate leg ulcers or traumatic wounds even in immunocompetent individuals. This case report highlights recurrent lower limb ulcers and cellulitis in a patient with type two diabetes mellitus, which was unresponsive to conventional antibiotic treatment. Histopathology revealed the diagnosis of cutaneous mucormycosis, and fungal cultures identified Rhizopus variabilis as the causative organism. Initial courses of oral azole antifungals yielded only partial response and he eventually required more aggressive treatment with i.v. amphotericin B and oral posaconazole. Good treatment outcomes for this condition require a high index of clinical suspicion, early histopathological and microbiological diagnosis, targeted systemic antifungal therapy, and surgical debridement if necessary.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cellulitis
/
Dermatomycoses
/
Diabetes Mellitus, Type 2
/
Leg Ulcer
/
Mucormycosis
/
Antifungal Agents
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Dermatol Online J
Journal subject:
DERMATOLOGIA
Year:
2024
Document type:
Article
Country of publication:
United States