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Predicting Adverse Events to Thiopurines in IBD: Are We a Step Closer?
Sharip, Mohmmed Tauseef; Parkes, Miles; Subramanian, Sreedhar.
Affiliation
  • Sharip MT; Department of Gastroenterology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.
  • Parkes M; Department of Gastroenterology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.
  • Subramanian S; Department of Gastroenterology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.
Inflamm Bowel Dis ; 2024 Jul 16.
Article in En | MEDLINE | ID: mdl-39011862
ABSTRACT
Thiopurines remain an important option in the treatment of IBD. However, the unpredictable and sometimes serious side effects and intolerance remain a major challenge. Pretreatment of extended genetic panel analysis, identification of novel variants, and monitoring of intermediate metabolites will help improve the overall outcome and reduce the toxicity.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Inflamm Bowel Dis Journal subject: GASTROENTEROLOGIA Year: 2024 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Inflamm Bowel Dis Journal subject: GASTROENTEROLOGIA Year: 2024 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom