Rhino-orbital-cerebral mucormycosis caused by Rhizopus arrhizus diagnosis via metagenomics next-generation sequencing: a case report.
Front Cell Infect Microbiol
; 14: 1375058, 2024.
Article
in En
| MEDLINE
| ID: mdl-39081868
ABSTRACT
Rhino-orbital-cerebral mucormycosis (ROCM) is a rare, invasive, and fatal fungal disease that is often easily misdiagnosed in the early stages due to the lack of specific clinical manifestations and adequate auxiliary examinations. Early diagnosis and timely therapy are essential for successful treatment. In this report, we presented a 46-year-old man with diabetes who experienced gradual vision loss, right ptosis, swelling, and headaches that progressively worsened to death within 4 days after admission. It was finally confirmed as a fungal Rhizopus arrhizus infection by metagenomics next-generation sequencing (mNGS). Our report has proved that mNGS testing should be strongly recommended in highly suspected patients.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rhizopus
/
Metagenomics
/
High-Throughput Nucleotide Sequencing
/
Mucormycosis
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Front Cell Infect Microbiol
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
Switzerland