Macrophages: A missing key in cardiac tissue engineering for sustained vascularization.
Cell Stem Cell
; 31(8): 1093-1094, 2024 Aug 01.
Article
in En
| MEDLINE
| ID: mdl-39094537
ABSTRACT
Macrophages regulate angiogenesis, repair, conduction, and homeostasis in heart tissue. Landau et al.1 demonstrate that incorporating primitive macrophages into engineered heart tissues significantly promotes long-term vascularization and cardiac maturation. This advance demonstrates the importance of resident immune-vascular microenvironments in cardiac tissue engineering, marking an important step forward for heart-on-chip technologies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Neovascularization, Physiologic
/
Tissue Engineering
/
Macrophages
Limits:
Animals
/
Humans
Language:
En
Journal:
Cell Stem Cell
Year:
2024
Document type:
Article
Affiliation country:
United States
Country of publication:
United States