Long-chain n-3 polyunsaturated fatty acid supplementation and neuromuscular function in older adults.
Curr Opin Clin Nutr Metab Care
; 27(6): 486-491, 2024 Nov 01.
Article
in En
| MEDLINE
| ID: mdl-39150439
ABSTRACT
PURPOSE OF REVIEW This review aims to explore the latest research investigating the effects of marine-derived long-chain n -3 polyunsaturated fatty acid (LC n -3 PUFA) supplementation on neuromuscular function in older adults. RECENT FINDINGS:
Ageing results in a decline in skeletal muscle strength and mass. There is growing evidence that LC n -3 PUFA supplementation increases muscle strength and mass in healthy older adults, yet the mechanisms underlying these effects remain elusive. Recent studies investigating LC n -3 PUFA supplementation have demonstrated effects on neuromuscular function such as increases in the compound muscle action potential (M-wave) amplitude and surface electromyography alongside increases in muscular strength. Therefore, evidence suggests that LC n -3 PUFA may elicit a beneficial effect at the neuromuscular junction and possess neuroprotective properties in older adults.SUMMARY:
LC n -3 PUFA supplementation may increase or maintain neuromuscular function throughout the ageing process. Further research is warranted to investigate the long-term effects LC n -3 PUFA supplementation on neuromuscular outcomes such as single motor unit properties and cortical/supraspinal networks, utilizing state-of-the-art techniques in neuromuscular physiology.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Fatty Acids, Omega-3
/
Muscle, Skeletal
/
Dietary Supplements
/
Muscle Strength
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Neuromuscular Junction
Limits:
Aged
/
Humans
Language:
En
Journal:
Curr Opin Clin Nutr Metab Care
Journal subject:
CIENCIAS DA NUTRICAO
/
METABOLISMO
Year:
2024
Document type:
Article
Country of publication:
United kingdom