An electrochemical aptamer-sensing strategy based on a Ti3C2Tx MXene synergistic Ti-MOF amplification signal for highly sensitive detection of zearalenone.
Food Chem
; 461: 140828, 2024 Dec 15.
Article
in En
| MEDLINE
| ID: mdl-39151347
ABSTRACT
A refined electrochemical aptamer sensing technique using PEI@Ti-MOF@Ti3C2Tx-MXene was developed for the sensitive detection of ZEN in food samples. A titanium-based metal-organic skeleton (NH2-MIL-125) was synthesized in situ using 2-aminoterephthalic acid as the organic ligand and tetrabutyl titanate as the metal center, followed by the simultaneous hybridization of Ti3C2Tx-MXene to synthesize a Ti-MOF@Ti3C2Tx-MXene composite material. These composites were subsequently functionalized with PEI and covalently linked to form a sensing platform on gold electrodes. Integrating a metal-organic framework (MOF) with MXene materials not only improved the electrochemical properties compared to those of individual elements but also decreased the stacking effect and increased the number of binding sites for the aptamer. The limit of detection (LOD) of this sensor was 1.64 fg mL-1. Additionally, the sensor could efficaciously detect ZEN in cornmeal and beer samples, exhibiting outstanding stability, reproducibility, and selectivity. This highlighted its effectiveness in applications in quality supervision and food safety.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Titanium
/
Beer
/
Zearalenone
/
Food Contamination
/
Aptamers, Nucleotide
/
Electrochemical Techniques
/
Limit of Detection
/
Metal-Organic Frameworks
Language:
En
Journal:
Food Chem
Year:
2024
Document type:
Article
Country of publication:
United kingdom