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Molecular imaging with 68Ga-PSMA PET/CT in high grade glioma: A biomarker for tumour neo-angiogenesis.
Usmani, Sharjeel; Riyami, Khulood Al; Numani, Shah P; Hashmi, Syed Furqan; Jain, Anjali; Sukaiti, Rashid Al; Ahmed, Najeeb; Shamim, Muhammad Shahzad.
Affiliation
  • Usmani S; Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman;Hull York Medical School, Hull, UK.
  • Riyami KA; Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman.
  • Numani SP; Department of Radiology, Carl T Hayden VA Medical Center, Phoenix USA.
  • Hashmi SF; Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman.
  • Jain A; Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman.
  • Sukaiti RA; Department of Radiology and Nuclear Medicine1, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman.
  • Ahmed N; Hull York Medical School, Hull, UK.
  • Shamim MS; Department of Surgery, Aga Khan University Hospital, Karachi Pakistan.
J Pak Med Assoc ; 74(8): 1552-1554, 2024 Aug.
Article in En | MEDLINE | ID: mdl-39160736
ABSTRACT
There are several promising radiotracers used for both staging and restaging of primary and recurrent brain tumours based on various mechanisms of tracer localization in tumour cells. 68Ga-PSMA PET has extremely low background uptake in normal brain tissue and consequently high tumour-to-brain ratio making it a promising imaging radiotracer for gliomas. 68Ga-PSMA demonstrates utility in evaluating high grade glioma during both initial workup or when suspecting recurrence. Herein the authors evaluate the role of this imaging modality and the potential future it holds in the management of high grade gliomas.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Radiopharmaceuticals / Molecular Imaging / Positron Emission Tomography Computed Tomography / Glioma / Neovascularization, Pathologic Limits: Humans Language: En Journal: J Pak Med Assoc Year: 2024 Document type: Article Country of publication: Pakistan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Radiopharmaceuticals / Molecular Imaging / Positron Emission Tomography Computed Tomography / Glioma / Neovascularization, Pathologic Limits: Humans Language: En Journal: J Pak Med Assoc Year: 2024 Document type: Article Country of publication: Pakistan