Your browser doesn't support javascript.
loading
Use of frozen native feces for fecal microbiota transplantation in recurrent Clostridioides difficile infection: a simple way to improve the efficiency of donor feces preparation.
Sintes, Rachel; McLellan, Paul; Navelli, Gabriele; Landman, Cécilia; Delage, Sandrine; Truong, Sandrine; Benech, Nicolas; Kapel, Nathalie; Moreino Sabater, Alicia; Schnuriger, Aurélie; Eckert, Catherine; Bleibtreu, Alexandre; Joly, Anne-Christine; Sokol, Harry.
Affiliation
  • Sintes R; Department of Pharmacy, Sorbonne Université, AP-HP, Saint-Antoine Hospital, Paris, France.
  • McLellan P; Assistance Publique-Hopitaux de Paris (AP-HP) FMT Center, Paris, France.
  • Navelli G; Paris Center for Microbiome Medicine (PaCeMM) FHU, Paris, France.
  • Landman C; French Group for Fecal Microbiota Transplantation (GFTF), Paris, France.
  • Delage S; Assistance Publique-Hopitaux de Paris (AP-HP) FMT Center, Paris, France.
  • Truong S; Paris Center for Microbiome Medicine (PaCeMM) FHU, Paris, France.
  • Benech N; French Group for Fecal Microbiota Transplantation (GFTF), Paris, France.
  • Kapel N; Department of Gastroenterology, Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint-Antoine Hospital, Paris, France.
  • Moreino Sabater A; Department of Pharmacy, Sorbonne Université, AP-HP, Saint-Antoine Hospital, Paris, France.
  • Schnuriger A; Assistance Publique-Hopitaux de Paris (AP-HP) FMT Center, Paris, France.
  • Eckert C; Paris Center for Microbiome Medicine (PaCeMM) FHU, Paris, France.
  • Bleibtreu A; French Group for Fecal Microbiota Transplantation (GFTF), Paris, France.
  • Joly A-C; Assistance Publique-Hopitaux de Paris (AP-HP) FMT Center, Paris, France.
  • Sokol H; Paris Center for Microbiome Medicine (PaCeMM) FHU, Paris, France.
Antimicrob Agents Chemother ; : e0073424, 2024 Aug 21.
Article in En | MEDLINE | ID: mdl-39166867
ABSTRACT
Preparing fecal microbiota transplants immediately after donation is resource-intensive, and a proportion are destroyed following abnormal screening results. We retrospectively compared two processes, frozen fecal preparation (FFP) and fresh native frozen preparation (FNFP), for clinical efficacy in the treatment of recurrent Clostridioides difficile infection (rCDI). FFP and FNFP were similarly effective with clinical success rates of 76.7% and 86.7% (P = 0.32), respectively. FNFP is an efficient procedure that saves resources while maintaining clinical efficacy in rCDI.
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Antimicrob Agents Chemother Year: 2024 Document type: Article Affiliation country: France Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Antimicrob Agents Chemother Year: 2024 Document type: Article Affiliation country: France Country of publication: United States